《英文msh詞典》Factor,Milk Growth
[入口詞] Factor,Milk Growth
[主題詞] Transforming Growth Factor beta
[英文釋義] A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development,cellular differentiation,hormone secretion,and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1,TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.